John Wayne as an anime-inspired space cowboy, blending rugged western charm with sleek sci-fi elements, set in a universe reminiscent of Cowboy Bebop or Trigun. Picture a lone gunslinger wearing a futuristic cowboy hat and high-tech boots, navigating through vast starfields and barren space outposts. His trusty revolver, enhanced with advanced technology, glints under the distant suns. Alongside him is a motley crew of space adventurers, each with their own unique abilities and quirks. Together, they pursue bounties and unravel intergalactic mysteries across dusty space towns and neon-lit cosmic cities, embodying the essence of a space western odyssey.