John Wayne as an anime space cowboy, blending rugged Western aesthetics with sleek sci-fi elements, wearing a futuristic Stetson and duster, armed with laser revolvers, roaming the galaxy in a spaceship reminiscent of a classic saloon, set against the backdrop of distant planets and star-filled skies, exudes an aura of grit and frontier justice, capturing the essence of legendary space undertakers from series like Cowboy Bebop or Trigun.